Microneedling with platelet rich plasma

Before we start explaining what microneedling with platelet rich plasma is, you first have to understand what is microneedling.

Microneedling is a cosmetic procedure that is widely opted for minimizing the signs of aging. The cosmetic treatment involves using a specialized roller with fine needles that pricks the top layer of the skin. This stimulates the new collagen production in the dermal layer. Since it promotes collagen production in the skin, microneedling is also referred to as percutaneous collagen induction or collagen induction therapy. It stimulates healthy collagen production in the skin that promotes faster healing of scars and other aging signs. 

Microneedling with platelet-rich plasma or PRP is the popular cosmetic treatment that involves using blood from the patients to revive the skin. The procedure reduces the length of redness and swelling caused after microneedling and improves healing.

Also read: Why should you use probiotics for skin care


What is the difference between Microneedling and Microneedling with PRP?

What is microneedling?

Microneedling with PRP

As we age, the levels of collagen and elastin in our skin decrease. This results in a loss of skin tone and elasticity. The result of it is wrinkles and sagging skin.

Microneedling is a non-surgical technique that uses a set of disposable sterile needles to vertically pierce the skin surface at a depth of 0.25mm to 2.00mm, depending on the problem we are trying to solve.

Unlike other products with microneedles, microneedling has a special vertical angle of the sting that enhances the effect and provides a more even and safer method, thus reducing the possibility of skin damage.

The result of skin penetration is the stimulation of the creation of new collagen and elastin that repair skin damage caused by old acne scars, wrinkles are reduced, hyperpigmentation is reduced and the skin takes on a more beautiful, taut, youthful appearance.

The effect of microneedling is not instantaneous because the skin takes time to heal naturally and create new collagen, but the results are long-lasting as the immune system accepts its collagen and elastin tissue instead of trying to attack or break it down as with synthetic or foreign materials.

The interval between treatments is 4 to 6 weeks. For optimal results, we recommend 3 treatments.

What is microneedling with platelet rich plasma?

Microneedling with PRP is also a cosmetic treatment used for stimulating collagen production in the skin. The difference is that it is performed by rolling fine needles over the skin and injecting platelets extracted from the patients’ blood.

The inclusion of platelet-rich plasma in the microneedling procedure makes it very effective. Since platelets promote blood clotting, it is effective for healing injuries and wounds. The platelets rich plasma has a higher concentration of platelets than the other components of blood. 

The PRP comprises proteins that promote growth factors in the skin and cytokines. It also helps in repairing the skin tissues naturally. First, the dermatologist will use the Microneedling process to prick the top layer of the skin and make invisible holes on the surface. Then PRP is injected through those invisible holes to promote cell reproduction and collagen production.

Microneedling with PRP vs without

Both micro-needling and PRP alone work well as a skin rejuvenation treatment, leading to similar results. However, when they are combined, the result of the therapy is better, as benefits are amplified and healing time is reduced.

Therefore, microneedling itself is good, but microneedling with Platelet Rich Plasma will lead to more improvements. This is because it delivers the platelet-rich plasma to the deepest layers of the skin.

Usually, 2-4 weeks after the treatment, some visible improvements appear. However, optimal results won’t be noticeable immediately after the first improvements. Usually, clients are satisfied with the results after 6 months with additional follow up treatments.

For most patients, the ideal therapy is a series of 3-6 treatments spaced 4-6 weeks apart. Although, some conditions could take up to 6-8 treatments for best results. Such as deep wrinkles, stretch marks, and extreme acne scarring.

How is PRP Obtained?

Platelets are small colorless bodies in the blood that we know by their role in clotting. When they are not active, they travel through the bloodstream. When an injury occurs, they are activated, gather at the site of the injury, branch out over the injured tissue, and thus begin the healing process.

The fact that they secrete active metabolites in their active phase means that they accelerate healing, ie they affect tissue repair, the reactivity of blood vessels and other blood cells in angiogenesis and inflammation.

Platelet-rich plasma is the volume of autologous plasma in which the platelet concentration is above normal levels. Plasma is the liquid part of the blood that contains protein, a little bit of lipids, and most of it is water.

Using a special needle, a sample of venous blood is taken, which is then separated using a special centrifuge system. In this way, 3 completely separated parts of the blood are obtained. There is a layer of erythrocytes at the bottom, platelets in the middle and plasma at the top.

PRP is an autologous therapy which means that there are no adverse reactions because the preparation is obtained from one’s own blood. Contraindications for PRP and microneedling with PRP are pregnancy and breastfeeding and people who are allergic to Bupivacaine (Marcaine). On the other hands, it can be used in patients with diabetes, in contrast to previous infiltrates with corticosteroid drugs that can raise blood sugar levels.

This is a 100% natural treatment and lasts about 45 minutes from the extraction and preparation of the blood to the treatment itself. Plasma is mixed with the anesthetic so that the treatment is painless, and it is injected with the smallest needles into the skin, leaving no traces of needle stings.

What is Microneedling with PRP good for?

Microneedling therapy usually serves to rejuvenate the skin and restore elasticity. It can be used to treat the following skin conditions:

  • scars (eg from acne)
  • freckles
  • wrinkles
  • stretch marks
  • enlarged pores
  • uneven complexion
  • reduced skin elasticity

Microneedling therapy can be applied anywhere on the body (such as legs with stretch marks, chest and back with acne scars), but it is most commonly performed on the face.

The most common use, however, is to remove acne scars. According to a study published in 2009 in the journal Cutaneous and Aesthetic Surgery, 72% of subjects with varying degrees of acne scars were very satisfied with the microneedling treatment using a dermaroller.

The second most common reason for choosing a treatment is skin rejuvenation and wrinkle removal. In a study published in 2005 in the International Journal of Dermatology, subjects underwent 6 treatments of microneedling therapy over 3 months. Satisfaction with the overall results related to skin rejuvenation after 3 months (reduction of wrinkles and improvement of skin texture) in the subjects was 80-90%.

Best use of microneedling with PRP procedure

The conventional microneedling procedure is used for treating almost everything. Ranging from wrinkles to age spots to scars and different forms of hyperpigmentation on the skin. When microneedling is combined with PRP, it boosts the procedure’s effects and enables the patients to achieve faster results as expected. 

Microneedling is also used for treating scars and stretch marks on other parts of the body, but microneedling with PRP is primarily used for the treatment of the face and facial skin. Medically, the procedure is termed as “Vampire Facial”. Almost every aging person is the right candidate for this type of cosmetic treatment. However, there are some contraindications to this treatment, and the procedure is not for people who:

  • Scar easily
  • Used Accutane earlier for acne
  • Are pregnant
  • Have different skin conditions, like rosacea or facial eczema
  • Undergone skin radiation in the past 12 months
  • History of poor wound healing 

What does microneedling with PRP treatment involve?

The microneedling with PRP treatment starts with a topical numbing gel that is applied to the treatment area to comfort the region. The treatment involves using small, fine needles to prick the surface of the skin. These controlled micro-injuries on surface promote collagen production as a part of the skin’ natural repair process. The excessive production of collagen results in the thicker dermis with the appearance of softer fine lines and wrinkles. 

In the microneedling with PRP procedure, the dermatologist extracts Platelet Rich Plasma from the blood drawn from the body of the patient. The blood sample collected by the doctor is centrifuged so that the plasma can be separated from white and red blood cells, and it is used for the treatment.

The plasma used for the treatment comprises a higher concentration of stem cells, platelets and growth factors. It boosts the healing of the tissues and promotes new cell growth. The invisible holes created by the Microneedling process promote better absorption and speed up the results. 

Benefits of microneedling with platelet rich plasma

Microneedling with PRP for facial rejuvenation

Microneedling with platelets rich plasma is considered the best cosmetic procedure for certain marks and blemishes on the face and body. Dermatologist prescribes microneedling with PRP to treat a variety of skin conditions, including:

  • Surgical scars
  • Acne scars
  • Sun damages
  • Wrinkles and fine lines
  • Hyperpigmentation
  • Large pores 
  • Uneven skin texture   

The inclusion of platelets rich plasma in traditional microneedling procedure accelerates the healing and stimulates skin rejuvenation while offering better outcomes than microneedling alone. 

Microneedling with PRP for hair loss

Microneedling might not sound like an appealing treatment. Also, given the youth and mystique around growth cell infused platelet rich plasma (PRP) treatments, people are often unsecure about these kind of treatments. However, the reality of using these two treatments together can result in a very promising outcome.

These two treatments are moderately effective individually. However, the combination of these two separate forms of hair loss treatment lead to excellent results. It can completely rejuvenate bald spots and lead to hair growth and revitalisation of scalp health.

Microneedling stimulates the release of growth factors in and around the scalp, which makes the platelets and the growth cells in the plasma to perform faster.

These treatments are suitable for treating a whole range of hair loss types. Even the combination of these two treatments are low-risk, relatively non-invasive and painless. The advantages are enormous, as skin is completely revitalized and hair follicles start to work again.

Microneedling with PRP aftercare

What to expect after PRP Injections

First thing that is important to say is that PRP injections are not any kind of fillers. There is some swelling after injecting the plasma, however, this swelling will subside and begin stimulating collagen production to the area.

So, what happens after microneedling with PRP?

Immediately following the procedure, the most commonly reported temporary side effects are redness, swelling, bruising, tenderness, tingling, numbness, lumpiness, and/or a feeling of pressure or fullness at the injection sites and/or in the treated area(s). You may apply cold gel packs or ice immediately after treatment to reduce swelling.

Microneedling with PRP aftercare for faster recovery

  • For 72 hours after treatment you should gently wash your face. Use a mild cleanser and tepid water and carefully dry the treated skin. It is important that your hands are always clean when touching the treated area, and do not scrubbing the injection sites with anything for at least one week after your treatment. After several days, you may return to your regular skin care routine.
  • We recommend serum antioxidants post-treatment, as its properties are ideal to help heal the skin by soothing and lessening irritation.
  • Following your microneedling treatment, your skin may feel drier than normal. The ideal ingredient to hydrate and restore the skin is hyaluronic acid.
  • Don’t apply makeup for 24 to 72 hours after the procedure. However, if you apply it then avoid makeup brushes, especially if the brush is not clean.
  • Use a sunscreen the following days after your procedure (we recommend you to use it every day even when you don’t do a procedure as part of your skincare routine to protect your skin from sun damage and premature aging).
  • Avoid direct high heat (e.g. blow dryer, sun, sauna, steam room, very hot shower, hot yoga, strenuous exercise, etc.) until the morning after treatment.

For a minimum of 5 hours after the PRP has been applied to your skin, do NOT:

  • Wash your skin
  • Expose the treated area(s) to direct high heat
  • Engage in activities that will get you wet or cause you to sweat (e.g. blow dryer, sun exposure, sauna, steam room, Jacuzzi, very hot shower, etc.)

How to maximize the results of microneedling with PRP

In the days following your microneedling treatment, and as the skin starts to regenerate, collagen-stimulating peptides are ideal to maximize the effects of the stimulation already started by the microneedling.

After PRP application, your skin proffesional may apply a topical antibiotic ointment or other soothing or healing ointments.

Starting on the evening of the treatment, wash your face gently with a mild cleanser twice daily followed by application of hyaluronic acid and then antibiotic ointment as needed.

Potential side effects and complications

The most common side effect after microneedling with platelet rich plasma is mild skin irritation, and redness of the skin that is possible a few days after the treatment. This is normal considering that small injuries occur during therapy. Some of the rarer side effects that can occur are swelling and dryness of the skin.

These side effects appear after the procedure and may improve in 4-6 days after the treatment. After the treatment, people have to avoid direct sun exposure and undergo any harsh skin treatment. Rubbing and picking the face should also be avoided.   

Since the microneedling with PRP uses your blood, the facts are that there is no chance of infection or cross-contamination. Infection or scarring is rare but can prove to be serious complications associated with microneedling with PRP. 

Talk to your doctor if you notice the following side effects:

  • bleeding
  • bruises
  • infection

Microneedling therapy is not suitable for:

  • pregnant women
  • people with skin diseases (such as psoriasis and eczema)
  • persons exposed to chemotherapy or radiotherapy

Avoid this treatment if you have open sores on your face, acne, or infections (such as herpes).

When to expect results after the procedure?

Usually, 2-4 weeks after the treatment, some visible improvements appear. However, optimal results won’t be noticeable immediately after the first improvements. Usually, clients are satisfied with the results after 6 months with additional follow up treatments.

For most patients, the ideal therapy is a series of 3-6 treatments spaced 4-6 weeks apart. Although, some conditions could take up to 6-8 treatments for best results. Such as deep wrinkles, stretch marks, and extreme acne scarring.

The traditional microneedling procedure with PRP can significantly improve the scars on the face, but evidence of the procedure is still inconclusive. However, many studies are inconclusive about the efficiency of the procedure in facial rejuvenation. The only pitfall of the procedure is the cost, as it is quite expensive than other cosmetic treatments.

The effectiveness of microneedling with platelet-rich plasma still needs to be better studied. Patients are likely to undergo several sessions to see results. After completing the course of treatment, patients have to follow the doctor’s guidelines for optimal maintenance based on the indication of the treatment. If you need any maintenance session, your doctor will let you know about it.

Remember, microneedling with PRP is the more expensive procedure than the microneedling alone. Some people may see positive outcomes with regular microneedling procedures without having to include PRP in the treatment. We suggest that patients consult doctors and dermatologists to discuss all potential treatment options to find the best-suited procedure for their specific skin condition.

Home microneedling therapy

There are dermarollers on the market that can be used at home, and they are presented as a cheaper, more affordable and less painful version of the treatment. The biggest difference is that these devices have blunt and shorter needles (up to 0.15 mm) because they are not intended for use by healthcare professionals.

Such home microneedling therapies do not have nearly the same effect as dermatologist therapy. Home dermarollers do not “pierce” the skin deep enough and therefore cannot achieve an equally good effect. Also microneedling with PRP at home isn’t possible.

Home microneedling therapy usually only stimulates circulation, which refreshes the complexion. Don’t overdo it with home microneedling therapy. It’s only recommended once a month to give your skin time to recover.

If you choose this option, follow the instructions on the package carefully. It is important to clean the device thoroughly after use to reduce the risk of infection.

Vampire facial/microneedling with platelet rich plasma experience


The reviews for microneedling with prp are showing that the benefits are visible when comparing the before and after, mostly on wrinkles and acne scars. But micro needling showed results even for hyperpigmentation.

If you can afford such a treatment, then we can tell you that microneedling with platelet rich plasma is definitely worth it.

Unlike other products with microneedles, microneedling has a special vertical angle of the sting that enhances the effect and provides a more even and safer method, thus reducing the possibility of skin damage.

With microneedling skin treatments, you can achieve fantastic results and a fresh and youthful appearance of the skin. For the first results of the treatment, it is necessary to set aside at least 28 days, and the maturation of new young skin lasts up to 2 years after the treatment.

Also read: Natural cosmetics from black coffee sludge


Please enter your comment!
Please enter your name here